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The Side Effects of Revolution Pet Treatment

 by amanda on 09 Jan 2013 |
99 Comment(s)

Only those who truly care about their families health, search for posts and articles like this one, which highlight the symptoms and potential side effects of different pet treatments. Which is why I know that you are a kind and compassionate person, who only wants the best for every member of your family.
And knowing that makes me proud to blog about the side effects of Revolution for cats and dogs, because I know that you will use it to compare against other pet parasiticide products, so that you make sure you get your pet's the highest quality of pest deterrent available.
Now, to start us out, I've always felt it's best to get the worst out of the way first. So let's discuss the worst potential side effects of Revolution Pet Treatment (as well as most other treatments available today).
If you notice your dog or cat showing signs of any of these symptoms, call your vet right away:
Muscle Weakness/In-Coordination - In 1% of clinical trials, some pets experienced extreme muscle weakness which lead to difficulty standing or walking. This can happen if your pet gets too large of a dose, or if they have a natural undiagnosed allergy to anything in the treatment. If this happens, your pet will need to see a vet right away. Because of this risk, it is always best to try any new pet treatments in the morning, so that if any adverse reactions appear, you will have plenty of time to get your pet into a vet within the same day.
Rapid Breathing/Panting - Because Revolution enters the blood stream, it can sometimes have a negative effect on your pets heart. In a small minority of pets, this can cause hypertension, which can lead to stroke or heart attach. If you notice these your pet is panting excessively or breathing very rapidly, take them into the near vet as soon as possible.
Muscle Tremors - If you notice that your pet is shaking uncontrollably or experiencing heavy muscle tremors, call your vet and schedule an appointment for as soon as possible.
Skin Burning - Out of 1743 animals tested, less than 2% had an adverse reaction that caused their skin to burn after application of any chemical pet treatments. If you notice that your pets skin appears is covered in a rash, peeling or your pet seems to be in great discomfort around the application site, you will want to take them into a vet right away.
Most of these reactions rarely occur in 5 out of 100 animals, meaning that it is not likely that your pet will have a serious reaction. Though being armed with this knowledge, helps you care for them if they do happen to be a part of the 5%.
And now that we've gotten through the tougher parts of this discussion, let's cover the more common side effects and some ways that you can help your pet cope with them, while the treatment relieves them of pests.
Temporary Hair Loss - More often then not, this happens with animals who already have sensitive skin, and with most of those cases, the sensitive pet is even more in need of pest treatment than pets who are not so sensitive. Though because the pet has sensitive skin, they will sometimes lose some of the fur around the site where you put the treatment. So long as they do not appear to have been burned, they should regrow the hair within a week or two at most.
Digestive Upset - Diarrhea, vomiting and stomach upset are the most common digestive side effects. They can cause your dog or cat to not want to eat or play for a little while until their body has processed the parasiticide. You can help them through these side effects by making sure they drink plenty of fresh distilled water, which will help keep them hydrated and help them process the treatments more easily.
Hyperactivity - When Revolution enters your pets bloodstream through their skin, it can sometimes cause them to have an elevated heart beat, as their body deals with the treatments reactions. This will make them anxious, as they will not be sure about what is happening to them, and that is usually what causes the hyper activity. You can help keep them calm by giving them their treatment in a dark and quiet room, and then staying with them for at least 30-45 minutes after the treatment.
Drowsiness - On the other side of the coin, some dogs and cats have seen the alter-reaction to hyperactivity, which is Drowsiness or Lethargy. As their body gives into the process of the pest treatments, they might need to sleep while the battle between bugs and love, wages on. If your animal finds themselves with this reaction, the best thing you can do is to help them get comfortable, and then check on them from time to time, to make sure they are still able to get up, walk around a bit and drink some water.
Drooling - It is recommended that every pet who gets a dose of Revolution, gets it right between their shoulder blades, to prevent them from ingesting the medication. That being said, we all know that our pets have a way of reaching the spot, no matter how crafty you try to be, and that means that there is still a chance that they might ingest the treatment.
When this happens, it most often causes excessive drooling as their body works to get the taste and the chemicals out of their mouth. You can help your pet through this by offering them plenty of fresh water to drink.

In most cases, the worst you're going to see is a displeased cat or anxious dog, whom are not very happy to have been treated, but who will be very happy in an hour or so, as they are finally flea and parasite free again.


Dinah - Comment
Dinah31 Jan 2013Reply
Are these symptoms exclusive to Revolution or are they the same for all flee treatments? I'm asking because an effective flee treatment is necessary. I've tried the "natural" ones to no avail and was told by a holistic vet that there is no effective alternative.
Pet Bucket - Comment
Pet Bucket31 Jan 2013Reply
This is pretty typical results for all flea treatments. Whilst they can differ slightly depending on the different main ingredient. You'll find they all have a very small portion of animals reacting in similar ways. It's just like some people react to Penicillin even though it's the most common old school antibiotic ever used
A general statement but the post was mainly to help people be aware of any possible side effects so they can take action.
Brenda Golovchenko - Comment
Brenda Golovchenko17 May 2013Reply
I gave me dog a Russian Bolonka the Revolution and three hours later he had a seizure, blood was taken and now shows signs of a blood infection. Could this have happened from the Revolution.
Robert - Comment
Robert18 Sep 2013Reply
I have 4 different breeds of dogs,
3 of whom show no side effects of Revolution, I got a Beagle in the month of Nov 4yrs old, clean bill of health, in April started to give Revolution to the beagle and couple days later had his first siezure that I know about, called previous owner - never any history of seizures.
I did not put two and two together until the 3 time I gave him revolution, and always about 2-3 days after he has a seizure, I actually even skipped a month of no medicine and no seizure.

I read up on the internet and in some cases - Yes, there have been incidents of reported seizure. I am going to contact the company that makes this in inform them of my findings. Btw the beagle is still healthy afterward, vet says nothing I can do for the seizures, just be there for your dog. No more Revolution for my pup.
Leanne - Comment
Leanne10 Jun 2014Reply
My 2.5 Boxer collapsed lastnight. I applied Revolution on him the night before. My vet ASSURED ME it was safe and very rare side effects. I thought I lost my dog last night as he collapsed. Thankfully he came back and rushed him to the hospital. They couldn't find what was wrong I feel very strongly that this pesticide is the cause to his violent health change. :(
Of course vets won't push the possible side effects. These drug companies are in buisness with them and heart worm prevention is a million dollar buisness
Shelley - Comment
Shelley08 Jul 2014Reply
Gave my Chihuahua a higher dose this time is what they gave me cause he gained a few pounds and he was panting all day in a cool car while I was driving. This was unusual for him, he is sleepy quite a bit, he is after 3 days still itchy, I found 2 fleas on him last night. This stuff is expensive for 4-5 drops of liquid. I think too much of my dog to give it to him again even tho he has had it before. No more resolution.
Scott - Comment
Scott14 Jul 2014Reply
Since applying this product, my otherwise healthy cat has vomited once and subsequently developed extreme lethargy, anorexia and fever. He is an inside cat and never goes outside. Took him to the Vet who totally ignored the possible connection between Revolution and my cat's symptomatology. Blood work showed only slightly decreased lymphocytes; everything else normal. Cat is dehydrated and fluids have been subcutaneously administered twice now. Cat still is not eating or drinking and sleeps all the time. For an otherwise healthy 6 year old cat, the connection between Revolution and his symptoms is too strong to ignore. I will not be using Revolution again and will not take my cat back to this particular Vet. Have no idea how long these symptoms last and the websites I have looked at do not address the issue, just as the Vet did not.
christina - Comment
christina04 Sep 2014Reply
Although Revolution can cause side affects, its proboaly the most safest method out their. Ive seen alot worst side affects. It really depends on the pets reaction to any of it. If their allergic to certain ones then bad things can happen. I don't suggest Hartz, Seargents or sentry at allll!!!! I have 4 cats and have applied to a others aswell, and no allergic reaction with revolution at all.
Pamela Riek - Comment
Pamela Riek04 Oct 2014Reply
I am a professional petsitter/animal care person and whenever I have seen revolution applied to elderly cats it is basically a death sentence. I had in my care some young, 3 years old, purebreds, a Bengal and a Havana Brown. Both developed urinary problems. The Havana seriously but he seemed to be predisposed. I notice they advise "distilled" water which is lower in mineral content--to prevent urinary crystals I suppose, which means they know this is a problem and already an issue with certain breeds of male cats especially. And I've seen Revolution used on indoor cats which are not exposed to heart worm risk!

I advise organic flea control and Frontline or Advantage only if absolutely necessary. This stuff only works the first week, so flea hygiene is absolutely necessary whether you use toxic assist or not. Sunlight or UV light kills eggs and larvae in 30 seconds of exposure. Flea traps work! See my blog on organic flea control at
Christine - Comment
Christine22 Oct 2014Reply
What about constant itching? I just put this on my bichon frise today and she has been constantly itching. I feel awful. This has happened with other topical flea treatments with her before, but my vet thought she could handle this one.
Kim - Comment
Kim06 Dec 2014Reply
I applied the small dose Revolution to my 10 yr. old Yorkie one week ago. The day after I applied it her little 8lb body looked swollen and she seems to be in pain when she walks. She has always had allergies and will cough up drainage but since applying the Revolution her cough is different, almost painful for her and more often than normal. She shakes a lot like she does when she is in pain. It has been a week since I applied the Revolution and she is still having same issues. Has this happened to anyone's little angel and if so what can I do to help her?
Dan - Comment
Dan28 Dec 2014Reply
I have given my dog 2 doses prior to the one yesterday he was fine with first two. Yesterday I applied revolution to my 84 lb golden retriever and his fur was stiff he was panting terrible and shaking his head from side to side. Rushed to vet who said he was having a reaction this was 6 hrs after first applied. Vet said wash area with soap and water and he gave him prednisone and cortisone shot. Now dog has to be on prednisone for 2weeks. Has anyone else's dog gone through this?
Lori - Comment
Lori27 Jan 2015Reply
Our 7 mo. old puppy has had Revolution since his first treatment with the breeder efore we brought him home at 8 weeks, He is now 23 lbs and the Revolution dosage is for 20.1-40 lb. dogs. we gave him the reatment and he has been lethargic, panting and just plain mopey, dopey and listless...I'm hoping today is a better day.
what do y'all do about the large difference in weights for the RX?
Vicky - Comment
Vicky28 Jan 2015Reply
I put Revolution on 2 of my cats 2 weeks ago. One seems just fine. The other has a large area of hair on her side and belly that she's apparently chewed/licked ??? off. This is the second time this has happened to her. The first was when we introduced a new cat to the house. I thought it was a nervous reaction to that. Now, I'm suspecting it may have something to do with Revolution. The hair loss is not near where the application of the medication went. I don't plan to use the product again.
Dan'L - Comment
Dan'L29 Jan 2015Reply
I put Revolution on my cat 4 days ago. She has not been the same..she is like your puppy Lori..mopey, dopey and listless. How long does this last? They gave my cat the dosage for a cat weighing 5-15lbs. I feel that my cat has been overdosed. Took her to the vet yesterday...they would not make the connection that this has anything to do with the Revolution. I will never use this product again. My cat hasn't eaten and is drinking very little water..when I bring it to her. She has stayed in the closet for the past 4 days. Please someone tell me how long this will last?
Liz - Comment
Liz25 Feb 2015Reply
I gave my 6 month girl cat revolution three day ago.. few hours after administering the flea med, she starting puking every where and then would not eat, when she drinker water, she would throw up.. After two days I.. took her back to the vet. They washed the site of application, gave her iv, nausea shot and another shot.. told to take her home and see if anything changes to the norm. She is now eating, but still throwing up afterwards. So of course now they want me to come back for xray and bloodwork. My cat xenia is healthy and still playful..she just can't keep anything goes down. I will NEVER use revolution again.
Nicole Whigham  - Comment
Nicole Whigham 28 Feb 2015Reply
Just gave my Miniature Pinscher a dose of Revolution a week a go and he has been having head tremors ever since. I can't say for sure, that is is the Revolution causing this, but in three weeks from now if these tremors stop. I will tell everyone I know not to use this product.
Carolle McCutchen - Comment
Carolle McCutchen09 Mar 2015Reply
Gave both my cats Revolution, one being 20 lbs was sick but got over that.Now 2 wks later my older cat is still bring up and had the runs really bad.l feel so bad for her but they recommend because l live in an apartment building and have had huge problem with fleas and ticks that they be on this every month.l will consult the vet because she is just about 12 and she has a sensitive stomach because Siamese cats can't tolerate it as well.l feel so bad that she is this sick.The whole building needs to be sprared because other just care or look after their pets.
Susie - Comment
Susie02 Apr 2015Reply
I applied Revolution two my year old cats for the first time. The cat that goes outdoors often had no reactions. The cat that stays indoors possible had a reaction. I didn't put two and two together until after the fact. A few days after the application she acted sick. We found vomit (presumably the sick cat) and she laid around with no energy acting sick. She drank water and ate food but just laid in one spot all day. a few days later when she started to act well i noticed a big scab on her neck around where i put the application (it could have been the exact spot but i really do not remember). what would be a good alternative Med for heartworm?
Tracy - Comment
Tracy05 Apr 2015Reply
revolution has sucked the life out of my 8lb chiwawa.
Muscle pain. Shaking uncontrollably.
Lethargy. I just hope he comes to back to his normal self. Very sad. :(
Barbara - Comment
Barbara10 Apr 2015Reply
Gave my five year old cat revolution 5 days ago, a day after application he became lethargic and had a fever not eating as much as usual. took him to vet they did blood work ( still waiting for results) gave him fluids and drug for fever. He doesn't look any long does this last?? Has anyone lost a cat with this drug?
Erin - Comment
Erin13 Apr 2015Reply
I applied Revolution to both of my cats twice. They are both 1 year old. The first time I applied the revolution on them, the male had developed cold-like symptoms with sneezing, watering eyes and nose but I figured it was probably from the vaccination he received through his nose while at the vet. The second time I gave Revolution to both of my cats, the cats both fought as hard as possible to not have it applied to them. The day after I applied it to the male, he developed a bald spot in the exact same spot behind his neck/between his should blades that the Advantage was applied. This spot was white at first, then turned bright red, then bloody and eventually scabbed and would keep on going through bloody and scabby phases.The spot kept itching him for weeks and he eventually developed another bald spot next to the original one. It was terrible because for weeks the scab would get scratched off and then become a bloody bald spot and took a long time to heal. He seems to be much better now but I was scarred that the bloody spot would eventually get infected due to his consistent scratching. Now I need to find a new flea medication that he doesn't have such a painful and irritating allergic reaction to.
Jamie - Comment
Jamie13 May 2015Reply
I bought Revolution and applied it to my two cats for the first time this past week. One of my cats is 15 years old and the other is 8 years old. Both are very healthy for their age, and are about the same weight - give or take a pound or two. I used the recommended dosage on both cats the same night. It's been a week since that night, and I've noticed two very different responses from each cat. My 15 year old cat acts totally fine - no symptoms of any kind. My 8 year old, on the other hand, has been acting very lethargic since it happened. I noticed a bald spot where the application was applied as well, so I called my vet. She said it could be a side effect and to bring him in, but it would cost $44. I spent over $100 on the flea medicine that made him sick...I told her I would wait a couple more days and see how he acts. I haven't seen him throw up or have any seizures so far. He just acts very lethargic...he doesn't really do anything but lay and sleep all day. He also doesn't eat near as much as he normally does. I bought some soft food to try and get him to eat, as they mostly eat hard food. He eats, but only little servings. This past night I went in my room and he was laying under the bed - he never does that. I'm not sure what to do...I hate seeing him like this and he has me worried. I've read the comments and a lot of people said the vet didn't make a difference. I don't know if I should just continue to see how he acts and hope he gets better, or go to the vet. I do know I'm never using it again on him. Please, for anyone that has dealt with long does it take for the cat to get better? Any other insight would be much appreciated!!!
Ah - Comment
Ah13 May 2015Reply
i have been using revolution for my two dogs and 7 cats for many years without any issues. Prior to this, we used advantage because I worked with the docs as a Foster mom and advantage is much easier to buy, split and use on younger animals. But I always found that the animals got slightly lethargic with advge.... And it's life expectancy goes down every time the animal swims or is bathed. Generally, with revolution, it is the safest flea/ tick/ worm med out there as long as you apply correctly- and not on broken skin. If your animal has bad fleas and has been scratching- the carrier component - small amount of alcohol can cause skin irritation and the hair will fall out. Likely, the animal was scratching and had underlying skin irritation to begin with.... It's hard to see the small rashes until they get irritated and then you see possible scabbing and hair loss which will heal as long as you stay on a good flea remedy and don't get reinfested :). I have found that if there is a reaction to the revolution- it is within hours of the medicine being absorbed- as within 2 hours it is safe to touch your pet. If it is days or weeks later - you may be confusing medications- advantage can be washed off anytime and make it less effective. The pet store topical (on the neck) brands should NEVER be bought- and I know people are going to get angry with me and say it works with no side effects for them (great for them) but always get flea treatments from your vet. And last, simply- symptoms may be a result of no fleas. Anemia, scratching and scabs from old bites while they heal. Imagine having thousands of these critters on you sucking your blood and smaller animal- less blood? You would be tired too!!! Lastly revolution is 99% effective in killing fleas, larvae and eggs on animals and in the environment advantage only kills flea adults that BITE your baby so they keep suffering while you get rid of the fleas. You do the math. Revolution is a good product- advantage is a great 2nd choice. Never buy from the pet store it's not the same! And yes there are always exceptions just like a person can be alergic to penicillin - a dog can be sensitive to a flea remedy but don't discount it on the first try. Your first month may be flea bite reaction or application error- ask your vet for help. Good luck and luv to all fur babies out there!!!!
Deborah Spiggle - Comment
Deborah Spiggle29 May 2015Reply
I gave revolution to my 1yr old cat about month and a half ago and he developed a staggering walk and does not hold his tail up. I am hoping that he will get better as it ears off he walks a tad bit better looks like a raccoon sometimes he has no control over pooping and peeing. His sister was given it at 9 months old she started having seizures and had to be put to sleep I ask at that time if it was the revolution or the vaccine she was given the vet said no but I had not been having problems with her like that and the day before at her appointment was told how healthy she look. Does anyone know when and if this will wear off or is his condition permanent?
Linda Stidem - Comment
Linda Stidem03 Jun 2015Reply
I gave my 13 1/2 yr old Maine Coon Revolution on Sat. April 11. He seemed to be fine that night . I worked all weekend but came to check on my cats several times. I got home Monday morning and have to leave on a family emergency. Did not notice him acting strange, but it was early morning and he was sleeping. I got back home on Thursday night and he was staggering in his hind legs. They just didn't seem to work. Took him to he vet, was told he had a damaged disc and possibly neurological problems. He steadily got worse. Would not eat or drink. Tried giving him subq fluids, but he lost all feeling in his front paws and then his back legs failed. I had to hold him in the litter box. Severaltrips to the vet for x-rays and blood work and was told he might have had a stroke and was throwing clots. I had to have him put to sleep on May 12, he could not hold his head up and had no feeling in his paws at all. He was fine before I tried that one dose of Revolution. I had always used Avantage but my vet said that they dropped it because they were the same thing and didn't want to carry both. I did not make the connection before but now have started to wonder if it was that dose of Revolution. I will not use it on my other cats again even tho they didn't seem to be affected by that first dose. I just can't take that chance.
Vikki - Comment
Vikki05 Jun 2015Reply
I have 5 cats all do fine but 1. It says nothing about being the cause of seizures but it has never happened before revolution. Of course she is the 1 with a flea allergy. Any suggestions would be appreciated.
Kelly - Comment
Kelly19 Jun 2015Reply
My 5 year old female spent all of last summer digging at her nose and ears. She had sores and scabs on her nose, ears, and even her belly. The vet sent in a biopsy of the skin that was reacting. The results came back as an allergic reaction. I never even thought that the reaction could be due to the revolution until this spring when I used it on her for the first time (I don't give it to her in the winter since she doesn't spend much time outside). She resisted strongly to the application (and there was no broken skin). She also seemed very sensitive when I touched her there for the rest of the week. So I started googling Revolution and now intend to stay away from it and see if her skin clears up. I'm up for anything holistic - fleas are better than torturing her with this drug!
Lana - Comment
Lana21 Jun 2015Reply
I really feel like I should share my story in case anybody is in the same situation. I read this blog, and many others, looking for adverse side effects of Revolution for my 10 week old kitten that we just adopted. She had mites. We took her into a holistic plus conventional vet clinic for a "kitten checkup" after I discovered mites in her ears. She was giving a single spot on applicaton of Revolution (so was my other cat, who had contracted them after just a few days, who is a perfectly healthy 1 year old cat that eats a raw food diet.) My kitten was treated on June 10/2015. After just a couple of days I noticed my precious little kitten had totally stopped eating, only slept, couldn't stand on her feet and was shaking profusely. I let this slide for 1.5 days and then took her to the vet. She wouldn't even smell food that was put in front of her. She would only sit and then lay down when stood up on all fours by me. The vet took her within an hours notice and said she had high fever, dehydration and a 'gassy tummy'. She was treated with a subcutaneous saline solution. We were given a homeopathic remedy of probiotics, aloe vera and slippery elm. That night I thought we were going to lose her. Her hind legs fell limp. She had a blank stare and no coordination. I force fed my kitten the medication I was given by the vet, plus honey water mixture, and a kitten formula that I got from a pet store. I really truly believe that my kitten was poisoned by Revolution. The adverse side effects of .05% of cats in the approved studies were her symptoms exactly. I nursed her with her medicine, milk, and honey water for two days straight, every chance I got, She regained strength in her hind legs. She even ate yesterday and today. I think my little kitten is going to pull through. Please, anybody who thinks their kitten or dog is having an adverse side effect of revolution, tell your vet right away and nurse your poor pet back to health. I read too many stories last night and the night before while I thought my baby kitten was dying in my arms to even consider anything else. PLEASE! treat your pet with saline solition, a probiotic, some kind of electrolyte solution (like honey and water) and force FEED them until they start eating again! This experience was horrific, I prayed and watched my poor kitten for 3 days now all night long and force fed her things that would help. Please, share my story. My kitten is pulling through. If your pet is not puling through try these remedies. I have never posted stuff like this but I feel like my story should be shared and everyone should know the potential risks of Revoluation.
May Read  - Comment
May Read 24 Jun 2015Reply
at 1pm today gave my cat 9 months old dose of Revolution treatment on back of neck .
About 4 hrs later , he had watery smelly poo, I bought this from our vets, on their recommendation that it was the best treatment..
Previously had bought the ones from supermarket , and had no problem .
I have " googled " revolution, and this is some side effects it causes ..
My poor Charlie , can't understand why he is locked up in laundry with his kitty litter !!
I have made sure he has clean fresh water, and hope he is better in morning.. Won't be using that product ever again ...
Vicky - Comment
Vicky25 Jun 2015Reply
I used Revolution on my two year old Shih Tzu on Sat. 6/20 and on Sunday afternoon she was lethargic. On Monday she started throwing up all her food and has had some lose stools. Took her to the vet on Tuesday but did not choose to spend a thousand dollars just to do some tests. So it is Wednesday and she is still very lethargic and not eating. I have gotten her to drink a little water by first putting it on my fingers and letting her lick it that way. I feel so bad that this has happened to her. Now she is throwing up again after that small amount of water.
Pamela - Comment
Pamela09 Jul 2015Reply
I gave my 3 yr old bulldog a dose of revolution on Sunday and a few hours later he started to have head tremor not eating or drinking water mopey without energy and his head feels warm does anyone know how long these side effects last I will not give him revolution again
Tony - Comment
Tony15 Jul 2015Reply
We began feeding a cat that just showed up to our house. We noticed it was developing a crusty rash. Similar to what our own cat had a year ago. So we gave this street cat a dose of revolution. Since it worked for our cat. We noticed that it was a bit skinny (under fed). It loved the cat food we gave it for the past days. The following morning, the cat is just laying there in the sun. It will drink very little water. No food. I picked it up and placed it under a shady tree and placed water next to it. I feel HORRIBLE. I wanted to do something good for a street cat that was very friendly. Now I may have just ruined his life.
not happy - Comment
not happy03 Aug 2015Reply
My dog passed away because the vet didn't give my baby the right dose....then tried to blame it on something else....4 hours after I administered this drug, she was throwing up, diharea shaking and walking into walls...please make sure ur babies are well taken care of.
Nlane - Comment
Nlane29 Aug 2015Reply
Whenever I put Revolution on my cats (one 4 year old, one 2 year old) they get sore looking, red, irritated bums, as if their digestive tracts are very irritated as well. This lasts about a week and a half. And yes I put the medicine on the back of their necks where it is supposed to go!
Cathy - Comment
Cathy03 Oct 2015Reply
I have 12 cats. I went to the vet yesterday with a dog that is allergic to flea bites. The vet suggested I use Revolution on all the cats because they mainly stay outdoor and Nexcare on the the dogs. Out of 12 cats, only one is having an issue and he is the one that has the allergic reaction to flea bites along with the dog.He is drinking and eating but has vomited a couple times. I administered all cats at the same time and 24 hours later, they all seem fine except one. I have a cat that is 17 and one that is 2 so that is a big range. I am hoping that they will be fine as I have never used this product.
Eve Moss - Comment
Eve Moss12 Oct 2015Reply
Hi, we have always used the Drontal for worms and the Advantage for flea's, NEVER had any flea's or worms to deal with. Then we got introduced to Milbemax and Revolution, flea's just continue, they do NOT die and the eggs keep hatching in waves. My 6 month old kitten after being given Milbemax and Revolution, is sick, lethargic, not wanting to eat, always trying to throw up, gaging, doesn't want to play, just sleep. Has bad balance and falls over sometimes. Those are 2 nasty drugs and they should be taken off the market, they make animals sick and these drugs DO NOT WORK on flea's or worms. I will NEVER use these drugs again, going to use Drontal and Advantage, very safe, NEVER had problems in all the many years we've had animals. The company that makes Advantage and Drontal has been around for MEGA! YEARS! and is a very TRUSTED COMPANY! And the drugs work GREAT & SAFE! for pets.
Laura - Comment
Laura25 Oct 2015Reply
Recently had to start using Revolution after moving to a new neighborhood and encountering zombie fleas that could not be killed by ANYTHING else (I tried EVERYTHING, people, I'm serious). Revolution worked, thank God. My cats were sleepy for a couple days and one seemed sneezy for a bit (probably unrelated) but otherwise fine.
andrea - Comment
andrea28 Oct 2015Reply
Thank you for all the comments. I chose to n it out of on after reading this
Catherine Krostek - Comment
Catherine Krostek09 Dec 2015Reply
I adopted a Pomeranian rescued from a puppy mill in Alabama. I have had Lilly since October 3rd. I noticed that she was shaking her body like she had just had a bath and brought her to the vet two weeks ago where she was treated with Revolution because the vet said she had ear mites. I brought her back to the vet tonight as recommended for a follow-up and they suggested a repeat dose, even though there weren't any live ear mites. I was a little worried since she is 13 pounds and but I let them administer a second dose at about 6:00 pm on Tuesday, December 8th because you have to trust your vet or there is no point going to them. At about 11:30 pm, Lilly's head started shaking back and forth. She didn't seem upset and the only thing I knew that was different was the dose of Revolution. Since my vet was already closed, I called the closest 24 hour animal hospital in the area and they said to watch her tonight and if it didn't stop or if she developed new symptoms, to bring her in or to my vet in the morning. Over the past 2 hours, I did a lot of research and found what she was experiencing is called "idiopathic head tremors" and saw videos of dogs with the same symptoms. The general information I found said to stay calm and the dog would not be upset and to try to distract the dog with toys or treats. I found that these symptoms often occurred after dogs were treated with heart worm medication. It is now after 1:30 am on December 9th and it has been happening on and off for 2 hours and sometimes wakes her up. I would be more alarmed but she even got up and ate while it was happening, and she is now sleeping next to me. I see that several people wrote with the same symptoms so I decided to share this. Thanks!
Angela - Comment
Angela05 Apr 2016Reply
I've been giving Revolution to my 15-year-od cat for a coupe years now, but after giving it to her tonight, she vomited. She has to be hand-fed but hasn't come to me for her scheduled feedings like she normally does. When I seek her out she does eat her wet food and is drinking water. I'm still watching her to see if this behavior continues into tomorrow. Has anyone else had this experience of a cat suddenly developing a reaction?
RW - Comment
RW14 Apr 2016Reply
I adopted a 6 month old cat last September and over the winter she developed some fleas. She also had some roundworms in her gut, which I discovered when she expelled some worms into the litterbox. It made sense, then, to try one treatment that could deal with both problems.
I had tried a cheaper flea treatment before which hadn't done much of anything (to the fleas OR the cat) but I did notice with the cheap one, that my little Smokey is flexible enough to twist right around and lick whatever you put between her shoulderblades. So when I got the Revolution, I put it in a spot I know she couldn't lick directly: between and slightly behind her ears. She's been totally fine with no reactions to the medicine (aside from freaking out when it was applied, but that was because it was a wet liquid and she hates wet!)
If your kitty is normally very good at contorting into odd positions, then I advise placing your flea medicine higher than the shoulderblades. Some of the symptoms people see could be from kitty accidentally ingesting the medicine when you're not looking!

If you need help treating fleas in the home, I recommend diatomaceous earth. It's a kind of soft rock crumbled into powder form (perfect for all you fans of natural remedies) and has properties that basically turn any insect's exoskeleton into a sieve. Your fleas (and other crawling insects) will die of dehydration as their bodies can no longer retain moisture, and it's one of the few things that works on the robust pupa stage of the flea life cycle.
Glenn McKnight - Comment
Glenn McKnight27 Apr 2016Reply
Been giving our two cats this treatment for about 6 years with no noted problems, Now the one cat about 8 years old and 16 pounds (using prescribe dose and one half per weight) has after 24 hours loss of hair and raised welt with redness at the application site about the size of a quarter. no other symptoms noted with both cats as described by the other posts here.
Teresa - Comment
Teresa10 May 2016Reply
Been giving my cats Revolution for several years now and have had no issues. Other flea treatments simply do not work. However, my late stepdad's car, who I "inherited", has shown issues with stomach upset. She is OK, but I was wondering if there is a recommended product for senior cats.
sharond - Comment
sharond09 Jun 2016Reply
All flea treatments attack the flea's reproductive and nervous system. If, as with human medications, an individual has a predisposition for that medicine to cause an adverse neurologic reaction, it will. Bear in mind that it is not the same for every animal, and all flea treatments, even the pills, carry inherent risks. Educate yourself in advance, watch for signs, and take the appropriate steps. It's not only Revolution which may cause adverse effects with your animal, it is every flea medicine or product out there. Aspirin can cause human deaths, but people still take it for headaches.
Kristin - Comment
Kristin20 Jun 2016Reply
I have used Revolution for years with no issues, but this last month one of my cats who is 13 years old lost his hair and seemed to have been burned at the application spot. He has been lethargic as well. I applied it to my 14 year old kitty last week, and we had to put her down Saturday morning. She started having very labored breathing and had fluid surrounding her lungs. There was nothing that could be done. I told the vet I applied Revolution a week earlier, but she didn't think that had anything to do with it. I feel so guilty. I think I may have killed my sweet girl by applying Revolution.
Kimberly - Comment
Kimberly22 Jun 2016Reply
Our new 8 week old kitten that we purchased from the Animal House in Morgantown died 5 hrs after being given revolution. Prior to the treatment she was flea infested and had been treated for worms. The meds for worms seemed to be well tolerated. But her stools were loose and became watery. They firmed up after the worm treatment for a day or so. After the vet checked the stool and saw there were no parasites, we started giving her probiotic which she seemed to tolerate ok. I woke up at 4 am last night and her the kitten calling out downstairs. I found her at the bottom of the stairs and her body was limp. She was still able to focus her eyes on me but her breathing was very shallow. Within 30 mins her eyes glazed over and her breathing was barely perceptible punctuated with sharp breaths and then gasping breaths. I called the emergency vet at 5 am but there was nothing they could recommend I do. I knew we were going to lose her. I stayed with her trying to comfort her and let her know she was not alone. She had her last breath about 6 am. I have never lost a kitten. I have no doubt that there was a connection between her death and the revolution. She had been weakened by her loss of appetite and loose stools. Now I have to tell my daughter who is away at camp. Echo was her kitten. So very sad!
Sandra - Comment
Sandra22 Jun 2016Reply
I have used Revolution for years. My previous dog developed lymphoma and died. I did not connect it to the Revolution treatments.
My 3 year old collie cross started having episodes when we played ball last summer. I believed it to be heat exhaustion. Then she started having seizures. All the bloodwork was normal. I don't give her the Revolution over the winter and she had no episodes.
I gave her the first dose 2 weeks ago and she has already had 3 episodes of staggering, panting and on 1 occasion fainted.
I will not be using Revolution again and will see if these episodes stop.

Nikki - Comment
Nikki04 Jul 2016Reply
I took my 11 yr. male cat to vet as he was going to the cat pan often n sitting there with small amts of urine when he did go so thought he might have urinary blockage, stones, or ? They tested his urine n said he had a urinary tract infection so gave him an antibiotic shot. They also suggested a Revolution treatment while he did not have a lot of fleas but showed flea dander. I've used advantage in past months but many say the fleas have become immune to it. After a few days home he was lying low n hiding then he stopped eating. I thought he was just healing from the UTI but then he started sneezing which he never did before & he even stopped drinking water n was getting weak n listless. Long story short I took him back to the vet but he started failing even more & I had to put him to sleep. I am thinking the Revolution affected him in a bad way on top of the fact that he already had a urinary tract infection. My other 16 yr old male also had the revolution at the vet while there for a check and he is ok, no bad reactions. I have heard good n bad about Revolution & some of the stories would scare u against using anything. Best bet is to discuss it with the vet n consider the basic health of the pet, and, or, other problems before introducing a new flea product.Clean the environment and try combing n grooming often.Also if u can sneak garlic into the food it helps to repel fleas, as well as certain aromatherapy formulas for a natural spritz on the fur and to treat bedding. Use caution, as certain oils can also be harmful so do your homework before using. Every animal is different, just as we as humans all react different to various meds n treatments. Research ahead of time to give your pet every good chance for a good outcome. They deserve it. Hope this was helpful in some way.
Sonia - Comment
Sonia03 Aug 2016Reply
I gave Revolution to my kittens after seeing worms in their stool. I have 2 kittens both from different parents, female 7 month old and male 4 months old. My vet suggested Revolution couple of times, and I said I will do my research and let you know. Finally because of the round worm discovery I decided to go with it after I had done my research and knew more about the product then the person selling it to me. I applied as instructed also watched video on youtube. Both of them didn't like it for first 30 mins kept trying to reach it to lick it and scratch it, however I had to keep them separate as well so they would not lick it off each other. After an hour or so they were back to normal. I have not noticed any behavioural change, except my 4 month old male has upset stomach and can't imagine that tiny thing can fart such a pungent smell. Its been a week, went back to Vet to for his follow up shots, and Vet suggested to give them Second dose of revolution after a week to make sure all the worms have been killed,
O-o ???
I wasn't sure if this has been done before, but something about that doesn't feel right to me, my regular Vet is on vacation will wait for his opinion. In my personal opinion we as pet owner are emotional about our pets, which are source of income for vets. They may seem like they care for animals and are animal lovers, maybe that once drove them to become a vet but its not why they are still vets, I mean they don't ask if we could do tests, no no no they tell you we are going to do all these useless tests and charge you for every tiny little thing... I don't mind spending money if it is worth it, but most of the time, they are just after making extra buck at the cost of your pets life. The way they handle them, the way they are giving them medicines without any second thought. As human body goes through up and downs, we sometimes require medicine and sometimes don't, our bodies can recover from few things, same with animals they have been living for long time as well, they know their bodies and have natural instincts. The way these vet describe one small decease is like it will be end of entire cat nation. My kittens never scratch themselves, but started to after visit to Vet, its like you car need a bulb change after it came from mechanic it needs 5 more things fixed.
Will keep you posted if there is any change in their behaviour or health, but I won't be applying it twice, its not like antibiotics that you take double dose first time.

p.s. I don't think pet owners should pay out of their pocket for their pets allergic reaction to the meds especially when it leaves them with pain or worse.

Good Luck
Dorothy - Comment
Dorothy22 Aug 2016Reply
Victor  - Comment
Victor 20 Sep 2016Reply
we have a senior cat and it seems after we put the revolution treatment on her she seems to get urinary infection, does that has anything to do with the medication. It's costing us a fortune in vet bills. another thing when we put her medication on it seem to irritate her eyes
Christine - Comment
Christine29 Sep 2016Reply
My 13 year old indoor cat with no fleas, mites etc. Was given the Vet recommend Revolution and within 24 hours. Stopped eating, drinking and just curled up in a ball all day.
Has had all sorts of tests and come up with nothing. The Vet does not believe it is from the Revolution. I am hand feeding small meals to my cat, forcing water and yes he has had fluids twice at the Vets. He does not want to stand, especially on his back legs . I am just praying that he gets through this. I will not be using Revolution again .
Kenny - Comment
Kenny29 Oct 2016Reply
I gave 2 of my 3 cats a revolution treatment. The third is to small to get it yet. Can she get sick from domino in contact with the other cats? As in playing around eachother or with each other
Wendi - Comment
Wendi31 Oct 2016Reply
I have 2 small dogs. One seems fine with revolution. The other who is very sensitive to everything shakes uncontrollably every time. I have only given it to her twice but same reaction both times. Will not give it to her again. Any suggestions?
Gina maxey - Comment
Gina maxey18 Nov 2016Reply
I gave my 12 wk old kitten revolution last night. Afterwards I googled it and found all these responses. I panicked, and couldn't find him to wash it off. He was sleeping somewhere.... woke up this morning to him being just fine. And I haven't found any fleas. I'm not promoting this product, just saying people are quicker to report negative effects than positive ones.
Lynn - Comment
Lynn19 Nov 2016Reply
I have a stray with eardrum rupture from ear mite infection, the revelution for mites left this kitty immobilized, hind legs non-functioning, vomiting everything, cannot keep water down, all of which began after 17 hours of dosing. No drooling, at first I thought she had licked it off, which is possible, she previously had head tremors, and neurological issues, possibly from previous reactions, stray cat, so not sure.
Alexandra Collins - Comment
Alexandra Collins31 Dec 2016Reply
I took my cat to the vet yesterday, she had what appeared to be "flea droppings" (little black specs that turn red when they hit water) but no active fleas. I can't find any in the house either, so the vet suggested a precautionary Revolution treatment. I wish I would have done research before I agreed. Since then she has been very lethargic.
I woke up last night to her sleeping on a pillow.. face down...I couldn't hear or feel her breathing. I freaked out and had to shake her awake, she then tried to purr after a while and started coughing like she was trying to get a hairball out. The following morning she refuses to eat or drink and just lies on the floor. I am very nervous after reading this forum!
I called the vet and they told me that lethargy is not a side affect of this drug...which is clearly NOT true. She also has fur and skin discoloration. This treatment is NOT WORTH WHAT HAPPENS TO YOUR PET!!
Norma - Comment
Norma04 Jan 2017Reply
I have given one dose if Revolution to my 12 week old kitten. She has had extremely watery eyes for two days. She had one bout of diarrhea after about 3 hours of the application. Has anyone else had this eye problem and how long did it last? This med was to treat ear mites but will NOT use it ever again!?
Claraboo - Comment
Claraboo12 Jan 2017Reply
If after administering flea medication or if your pet acts differently after bathed in a flea and/or medicated shampoo BATHE them immediately with dish soap. Blue Dawn dish soap is preferred but any will do to remove the product and rinse your pet thoroughly. Rinse them twice as long as you normally would. If you gave your pet an oral medication and they are acting differently please contact your veterinarian immediately.
lisa Reynolds - Comment
lisa Reynolds04 Feb 2017Reply
I had a very healthy cat, she rarely went outside and if she did it was only in the backyard. We had a problem with Flees, I was using Advantage which seemed to helo but the vet recommended revolutions. At this time we had 2 cats and a dog who were all on it. Once we switched to Revolution my cat had a skin reaction I didn't notice right away, so I stopped using it on all my pets. My cat started acting differently and she got huge lumps on her neck, close to where the medicine was administered, turns out she had gotten lymphoma which they say is being around other cats or outside. I find it off that it was in the same area as the Revolution, could this possibly be what caused this? I don't know but I had to put her down last month and I can't help but wonder. Miss my kitty though
Jess  - Comment
Jess 25 Feb 2017Reply
Its straight up poison. Two of my dogs started having seizures after we switched to Revolution instead of Heartguard. It was a delayed response and the seizures were a couple months later. The blood work came back normal and they were labeled as idiopathic epilepsy. Didn't give it to them for a few years after that and they never had seizures again. This year we gave it to them once at the end of heartworm season and sure enough both had seizures a couple months later. Coincidence? I don't think so! This is a neurotoxin and not all dogs have the ability to rid it from the system without suffering side effects (immediate or delayed).
Linda Smigelski - Comment
Linda Smigelski03 Apr 2017Reply
One of my cats was diagnosed with ear mites and prescribed Revolution..and since I have 8 other cats the vet said no doubt the other cats have ear mites so I ordered revolution. Gave it to all including Missy who is 10 years old this past Thursday a.m. and at 4 p.m. that day she was having a seizure...then she had another at midnight and again the next day at 7:30 a.m. Took her to the vet...blood work first reaction upon seeing Missy of course was shock and horror to see her thrashing so violently and my first thought was that it was a reaction to Revolution....ithe bloodwork showed no problem of Diabetes nor problem with liver or kidneys...could be heart problems or neurological, and will have mroe tests done. but in the meantime, she is not herself and having seizures..
Fran - Comment
Fran03 Jun 2017Reply
Gave my 18 cat revolution 2 days ago and she is sleeping all the time and staggering. She still has fleas! She is eating but can't even stand to use her box.
christine - Comment
christine13 Jun 2017Reply
I have an American Staffordshire terrier, he is 11 months now. I applied advantix spot on and noticed that his back hair (on spine) where I applied the spot on fell. I read that this could be a side effect from the spot. How long does it take for his hair to grow back?
sidney lucas  - Comment
sidney lucas 14 Jul 2017Reply
gave my 3 year old cat revolution a couple weeks ago he developed a lump on the side of his neck went to the vet gave him a shot of steroids and antibiotics . did ok for a few days now he is back to not eating or drinking not using litter and is sleeping 23 hours a day . he is a in door cat never goes outside . he weighed 17,6 lbs and now weighs 12,2 in a weeks time . and when at the vets blood work came back fine
Rosie - Comment
Rosie19 Jul 2017Reply
After 3 rounds of flea meds my 6 year old cat was never the same again and 8 months later he died :( RIP Mr kitty.
He lost weight lost his appetite became unsteady and one morning he woke me up crying and non responsive. Rushed him to the hospital where they told me they believed it to be a blood clot in his brain. I think it was the flea meds that killed him. My heart aches for him everyday. - Comment
grwillis617@yahoo.com31 Jul 2017Reply
My vet applied revolution to my 1 year old cat inside protected siamese cat and within 24 hour he had a temp of 107. He stayed in the vets office for 3 days on ice and more medications. I finally took him home and waited for him to die. I took him off of all of the medications that they had put him on and within 4 days he pulled out of it. My vet said there was NO WAY it was the revolution and 6 months later they really thought i should try revolution again. He died. When i called and went in to see the vet they asked me to not come back.
James - Comment
James18 Aug 2017Reply
A stray was mauled by a dog owner who doesn;'t leash.Took stray to my vet, he had to have surgery so he stayed there a week. I mentioned flea problem with my kitties at home. Vet recommended Revlution. I gave one kitty her dose, 5 days later, I got another four kitties their dose. The first kitty was lethargic until day 5 when her kidney was giving out, per a vet visit. He said feline leukemia. I put her down after a wonderful afternoon doing all things she loved. Been 3 days since I dosed the four kitties. ALL are lethargic, will not eat, walk, purr, or give me lovings. They best be ok or I will be having a serious convo with my vet. $850 later and possible 5 dead kitties. Will definitely be getting copy of the bloodwork papers on my one kitty who went to heaven on 8/15/17. I love you, forever, Mocha.

The STRAY CAT who had jaw surgery was in a week, so he didn't get a dose of Revolution.


James - Comment
James18 Aug 2017Reply
I read previous comments and saw the water/honey recommendation. Out of honey, so I used water/100% pure cane sugar, half of each, and have given two cats about 10 ml. each.

One is up walking around now, about an hour later and wanted treats. Other is still sleeping. Will keep this updated.
Linda - Comment
Linda31 Aug 2017Reply
I had been dosing my dog, Sadie, with Revolution since she was 6 months old. In June, 2016 she had her first episode. She lost coordination, couldn't walk, stiffened, then her head began to shake back and forth, she shook from head to toe. After about 2-3 minutes she returned to normal, but she threw up. She had another episode about 2 weeks later, then nothing for 6 months. Then it started again, about once a month. When I took her to the vet, the doctor said she needed to start anti-seizure meds. We both agreed to give it one more month. The following month I gave her the Revolution dose, and she had an episode about 5 hours later. And that's when it hit me. Could it be the Revolution? I spoke to her doctor, and he told me to stop the Revolution. She had a very mild episode about one month following her last dose of Revolution, and hasn't had one since. The moral to this story is, it took ME to figure out that Revolution was causing these episodes. Her doctor said that she is the first case he has seen with this reaction to Revolution. I hesitated to put her on anti-seizure meds because these meds become a life time commitment, and they only treat the symptom. After reading all the entries to this blog, I see that many dogs and cats have horrible reactions to this drug. It should be outlawed.
David - Comment
David02 Sep 2017Reply
Used the Topical Brevacto for medium sized cat yesterday only but to find my cat twitching and crying on the floor this morning. She was surrounded by fur and a large chemical burn on the back of her neck. Waiting for the Vets to open. Must be one of those <2% to have a negative reaction. !!!
Christi - Comment
Christi27 Sep 2017Reply
My 6 year old cat had the PU surgery and had chronic UTI's since. With being said I asked my current vet and my old vet if Revolution would be safe since he's not a healthy cat.. Both said yes. Almost emmediatley started having seizure like twitching and severe tremors in his head and front legs and he slobbers. This is now permanent and a year later he still has those issues. Always use your first instinct wish I had and never put it on him.
Islam Ashraf - Comment
Islam Ashraf10 Oct 2017Reply
The Cat Flea is one of the most dangerous abundant and widespread species of flea and the most common flea which feeds off cats and humans. So we should to know the kinds of treatment about the cat fleas, especially when we allow them to stay in our home, it would make a huge infection to us. Thank your for your expensive informations!
How To Treat Cat Fleas At Home in simple ways
Craig Talley - Comment
Craig Talley30 Oct 2017Reply
I did a first treatment of Revolution on two of my kitties for ticks. Both lost appetites and lethargic.
The largest cat, Rocky, the Maine Coon had a massive Seizure and vomited white foam after 4 days. He was very healthy and died horribly.
Just don't use poison like Revolution of you love your pets. My heart is so broken!
Jen - Comment
Jen06 Nov 2017Reply
I'm only commenting because so many people think revolution is causing seizures in their dogs but I doubt it. I had 2 dogs in the 1990s who both died of seizures and we never used flea meds on them. The only thing they got was yearly vaccines and heartworm meds.
delta - Comment
delta11 Nov 2017Reply
Took my cat to the vet they put revolution on the back of her neck that was October the 18th now she has a bald spot where they put it on her and it will not heal. Worst product ever.
John Czoykowski - Comment
John Czoykowski18 Nov 2017Reply
My lab sharpei mix dog started using Revolution when he was about 5. No problems for 5 years, but this month, starting about a day after I administered his monthly treatment, he had a seizure, grand mal type, legs paralyzed, back reverse arch and stiff. He's had at least 4 more this week. His health has been great, generally, but also just recently he started having trouble climbing stairs, and his energy level is down drastically. I suspected the Revolution, and after reading of similar symptoms here, now I see the pattern, and will never give him another dose. I hope he can recover from this episode.
Ingrid - Comment
Ingrid16 Jan 2018Reply
Like many others my cats have experience discomfort when having Revolution applied (burning, itch, hyperactivity) but I feel like I need to share as I see the effects reaching new highs.. A few months back my three indoor cats were all getting a monthly dose of Revolution (because, who wants fleas right?!) but I stopped due to the prolonged sensitivity and itch it would give one of my cats. Also, one morning a few days after applying Revolution to the cats I woke up with acne-like bumps all over my face and upper body. Nothing I have ever experienced before and that night my "itchy" cat had slept up against my neck - so I stopped Revolution thinking it might have caused this reaction to my skin. Fast forward 6 months, randomly I find one flea on one of my cats and no matter how much I brush I find nothing more than one. So I treat the house with peppermint spray, give all three a Capstar and a dose of Revolution. The itch and jumpiness sets in immediately. However, this time one of my cats doesn't stop scratching. Two months later she is still itching and has big pieces of dander all over her black fur. She even is scratching so much she starts bleeding under her chin. At the same time, I start to develop eczema/acne symptoms again and have to see my dermatologist again. This thing is poisonous to cats AND humans and you will never get the vet to admit that (I tried!)! It's their bread and butter!
Erica - Comment
Erica01 Mar 2018Reply
I found this was very useful to use for fleas that I had i my pubic hair.
Carol Siegfried - Comment
Carol Siegfried04 Mar 2018Reply
PLEASE EVERYONE, stop putting these poisons on your animals. All your pets symptoms are definitely from the flea medication. My vet applied revolution on my perfectly healthy 5 yr. old cat (3 applications) and now my cat is having an allergic and neurological reaction , hyper, agitation, running fits , licking biting , scratching, and losing his fur .
I will never give him any chemicals again. I'm using only natural alternatives going forward, and now I'm detoxing him with a all natural liver cleanse and probiotic and fish oil.
Carol Siegfried - Comment
Carol Siegfried04 Mar 2018Reply
Yes Ingrid,
You are right ,I had the same experiences with my cat , hyperness , running , itching , biting, and licking with flakes on his back.
Please everyone dont use these poisons! These damn drug companies dont care about our pets or us
Jennifer Lane - Comment
Jennifer Lane18 Mar 2018Reply
My vet insisted on giving my perfectly healthy cat revolution. 24 hours later same adverse reactions as all of the above people experienced only my poor sweet Ava developed Ataxia, a side effect stated on Revolution's insert. I would find her laying in her litter box as if she tried to go to the bathroom but then couldn't get herself out. The few times I saw her walk - or attempted to - she would take one or two steps and fall over to her side. She lost feeling in her front limbs - I applied the Revolution between her shoulder blades - so its a definite correlation as to why her front limbs lost feeling and she couldn't walk. One week later I found myself at the vet and there was nothing I or the vet could do but euthanize her. JUST two weeks before this incident and never being on Revolution, she had bloodwork, urine analysis, etc. performed and it all came back as perfectly healthy. So why did I have to put her down one week after applying Revolution? It was and is still - the worst event of my life and very difficult to understand and/or deal with. A medication that is supposed to help our animals yet it kills them. I'll never use these types of medications again on my 1 remaining cat and three dogs.
Ven - Comment
Ven12 Apr 2018Reply
I was worried my kitten had ringworm, and applied the Revolution near what was probably broken skin. It burned her skin deeply, Turing it leathery and still, after which it peeled off almost completely. On the earliest spots her fur is finally returning - but don’t apply near broken skin. She hasn’t had any other bad symptoms thank god, but it’s been weeks and she still has a big bald spot.
Kellie - Comment
Kellie15 Apr 2018Reply
My mom's 1 1/2 year old cat was given Revolution a week ago and is now severely anemic and lethargic, won't eat. It is so sad. She is rushing him into the emergency vet now for blood transfusion. So sad the vets won't even consider it being the Revolution, obviously they get a kickback. So my mom has spent well over a thousand dollars with no answer and not knowing if her cat will make it. I am sickened by these pharmaceutical companies.
Nine's Catudio - Comment
Nine's Catudio05 May 2018Reply
We just went through a real ordeal with our 2 babies - 10 months old and 9 years old (felines). The little one was treated 3 times, despite us trying to convince the vet it was not working. The older one was treated once and was sick for about 2 weeks. Severely sick and lethargic.
CHANGED VETS, CHANGED MEDICATION - all mite free and healthy now.
Nothing good can be named Revolution.
Island Girl - Comment
Island Girl02 Jun 2018Reply
I feel like I need to comment because I have been using Revolution on both of my cats for years and have never had a problem. Recently, I've found it doesn't work as effectively as before and that's why I was looking it up. But as to any side effects, none. It also used to work better than any other product at getting rid of fleas.
Ophelia - Comment
Ophelia30 Jun 2018Reply
I had a vet/doctor that overdose my rabbit with revolution. She gave him 2 months worth on him and I'm hoping he'll be safe. Been praying for him but there's not much I can do. So far he's ok but I hope nothing serious will happen. One thing for sure I'll never take him to that vet again
Leah - Comment
Leah05 Jul 2018Reply
Hey guys. I know this is a fairly old thread, but maybe someone can help us.

Did any of you ever have an issue with facial swelling in the days after administering Revolution or any other flea and tick treatment to your pets?
Kathy - Comment
Kathy22 Jul 2018Reply
A lot of these comments and there is so much confusion! I work for a vet for 20 years and they are not trying to push drugs for your pet. First, Revolution is a drug not a chemical, advantage and Frontline and topical products for flea and tick prevention are all insecticide based. They do not enter the bloodstream they stay in the top layer of the skin. Revolution is a heartworm preventative, a single parasitical drug that goes on to kill fleas for the next 30 days. It enters the bloodstream like any drug does. Of course some animals just like some people will have side effects from certain drugs. Have you not heard the commercials on TV followed by a Litany of possible side effects? The important thing is to be aware, and also know there are a wide variety of drugs available to address heartworm. If a animal has a reaction to one type of drug it's advised to use a different type of heartworm drug. Also keep in mind that heartworm is fatal. Heartworm disease is also a very expensive to treat and monthly heartworm prevention is always the better option. So if you feel your vet is trying to push medications on your pet, realize your vet is actually trying to save your pet from getting heartworm disease! Keep in mind that topical flea products sold over the counter are governed by the EPA Not the FDA. Always ask your veterinarian for the best topical flea treatment, veterinarians are knowledgeable about topical flea products that are effective and studied to be safe versus those that are on the Shelf at any Walmart I may not have any safety studies associated with them. Again, pets are individuals as people are individuals, and your pet may fall into the 1% or 2% of the population that may have a specific reaction.
Quacks - Comment
Quacks28 Aug 2018Reply
Did anyone have a dog where their nose went from black to pink? This all happened after I applied the one and only treatment to my 1 and 1/2 year old spayed female small dog. I read all the other causes for this, but since the day after Revolution treatment, I noticed the pink on her previously very black nose. Waiting to see if it goes back to black. It's been about a month now.
Phyl  - Comment
Phyl 09 Sep 2018Reply
I reluctantly put this on my large cat. The does was even a hair less than recommended. It burned him. He now has scabs and a half dollar sized bald spot. Shiny bald. It doesn't look like it will grow back. He was a true beauty before Revolution. This is a terrible scar. It even seemed to melt some surrounding fur. It is breaking my heart.
Slb - Comment
Slb23 Sep 2018Reply
My Maine Coon kitty is having muscle tremors since I applied Revolution. He is strictly indoors but I have a dog so occasionally he will bring in a flea and I will notice the kitties scratching. I will NOT ever use Revolution again. Take this product off the market and stop making people’s beloved pets sick!!!
Nate - Comment
Nate17 Oct 2018Reply
Vet switched us from Frontline to Revolution on 5 year old Border Collie. After 3 months dog started having seizures once a day. After we researched this on the internet we saw many complaints about this product. Bathed the dog with Dawn dish soap to get as much residual product off as we could. Seizures became less frequent and less severe after about 3 weeks. Changed treatment to Seresto collar for fleas/ticks and back to Iverheart Plus for heartworm. As soon as the supply runs out our other Collie is going off this product as well. If you have never witnessed a dog having a bad seizure, you won't want to chance using this product at the recommended dosage. It literally sent my wife off crying to our bedroom on more than one occasion.
Brenda - Comment
Brenda08 Nov 2018Reply
I gave my Ragdoll cat Revolution about 1.5 weeks ago. Since then he has lost all the fur on the underside of his leg. Now he is throwing up, lethargic and won’t eat or drink. This happened once before and he had $500 worth of tests to figure out what was wrong, but they couldn’t find anything. Now I know - it’s the Revolution. This product should be taken off the market and someone should sue this company for poisoning our pets.
jo - Comment
jo18 Nov 2018Reply
I have a feeling that the revolution caused hemolytic anemia and leukemia in my dog coco. If anyone else has experienced this as my dog was perfectly healthy and after the dose within days went down for the count. we are having to help her cross over this week after trying for weeks to get her rbc up enough to do surgery and a blood transfusion the meds would not work
angi-la - Comment
angi-la05 Dec 2018Reply
I have read the anecdotal comments about Revolution, but have not read one post that actually proved Revolution caused any harm. I have used this product for more than 10 years on five different breeds from toy to mastiff size. I have never had a reaction on any of my pets. Like all products, its very important to use the correct dose and to apply it in the area instructed so the pet can't lick it off. Especially cats! It is applied at the base of the neck in front of the shoulder blades, for the express purpose of the pet not being able to lick it. Also not to be used on sick, debilitated or underweight animals. Tests on cats....In safety studies, Revolution was applied at 1, 3, 5, and 10 times the recommended dose to six-week-old kittens with no adverse effects. In dogs... It was administered at 1, 3, 5, and 10 times the recommended dose to six-week-old puppies, and no adverse reactions were observed. Keep in mind this is not just a flea prevention product. It is also a heartworm preventative. Before using the pet should be clear of heartworm, and NO other heartworm product should be used. The active ingredient is a semi-synthetic ivermectin, which has been safely used by Vets on pets, and farmers on cattle, pigs, horses etc, for decades.
Nate - Comment
Nate09 Dec 2018Reply
If Revolution was not responsible for seizures in my border collie, (see above post) please explain why the dog has not had repetitive seizures since we have changed treatment. It is indeed Revolution that caused seizures in this particular animal. No further seizures have been noted since the product has been discontinued, no other changes were made in diet or other meds given prior or after Revolution. Revolution is to some animals as Penicillin is to some people. This is not anecdotal, it is fact. There is no other variable that could have created this issue that is known to us. While our other Collie appears to tolerate Revolution we have reduced the dosage to about 1/2 application. Who knows what other unseen damage may be occurring at the organ level. As I previously posted as soon as this product is gone we are changing our product to the aforementioned products.
Chances are probably 1 in 10 maybe a bit more your cat or dog will experience issues with this product, when you consider the amount of cats and dogs using this product that's a hell of a lot of sick animals. By the way how much were you paid to post that? Or are you Zoetis? And no I'm not here plugging Seresto or Iverheart but I'll be damned if I'm going to knowingly apply a product that causes harm to one of our dogs.
Jo - Comment
Jo16 Dec 2018Reply
Both my cat and my dog had a reaction to Revolution. My dog recovered after three days of vomiting, diarrhea, lethargy and stiffness in his hind end. My cat has suffered severe consequences. She had a week of not eating so I was able to give her subcutaneous fluids and force feeding. She didn’t want to move, she was very lethargic and strange stiffness again in her hind end. She finally recovered but then lost the function of her left hind leg completely. She will live but is now disabled. I have had many animals over the years including fostering many rescues and used many flea treatments but never had this reaction until using this product. Reading the studies on Revolution side effects it does talk about some animals having adverse effects. Selamectin is the active ingredient and is a neurotoxin which attacks the central nervous system, it is not meant to cross the brain blood barrier in mammals but does in fleas, etc. Unfortunately it looks like it will in some mammals, namely our pets, and causes the same poisoning as it does to fleas! There is no antidote but supportive care will give our pets the best chance to recover. Obviously I will not be using this poison again on my animals, I do understand that many pets are okay but after seeing the suffering it caused mine I won’t risk it on the others.

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